T-cell (TCR) leukemia & lymphomacontains CCAP BACs that span the known breakpoint regions
Many sub-types of T-cell leukemias are associated with chromosomal
translocations involving the T-cell receptor genes (TCRA, TCRB, TCRD and
TCRG). Because of the somatic rearrangement of the TCR genes that occurs
normally, these genes can accidentally associate with a proto- oncogene
in a chromosomal translocation, thus activating it, resulting in a
T-cell neoplasia. Below is a table of genes involved in these
translocations. This disease specific set contains CCAP BACs that span
the known breakpoint regions in order to detect disruption of the normal
sequence using FISH.
Clones are provided as a live culture in a 2ml tube. Each tube contains
LB medium supplemented with 8% glycerol and the appropriate antibiotic.
we will ship your order at room temperature via express delivery. Store
the clones at -80°C.
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