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Gene targeting vectors - Smithies

For engineering genomic sequence duplications and insertions/deletions in mouse ES cells
With these novel vectors, you wield unprecedented power in gene targeting experiments. Following insertion of the appropriate homology arms, duplications of up to 100 kb and deletions of up to 50 kb can be made, with precision down to a single base pair. This makes it possible to precisely duplicate or delete entire genes in a single experiment. Duplications can also be used to insert reporters, promoters, mutations, or any other sequence of interest into the genome. Finally, the same vector can be switched from duplication to insertion/deletion by simply rearranging the positions of the homology arms. Download schematic for further details.

The complete vector includes:

  • Selection marker (choice of neo, hygro, hprt),
  • Negative selection marker (TK)
  • Linearization sites
  • Two multiple cloning sites for oriented insertion of homology arms
Shipping Information:
Shipped at room temperature. Store at –20° C or –80° C.

 

 

Purchasing Information
Catalog No.
Description
Literature
MES3974
OSDupDel Gene Targeting Vector - neo
 
MES3975
OSDupDel Gene Targeting Vector - hygro
 
MES3976
OSDupDel Gene Targeting Vector - hprt.
 

 

 

For more information :: Bioxys and Gentaur BVBA :: Av. de l'Armée 68 B4 :: BE-1040 BELGIUM

Email: info@gentaur.com
 

International 

+32 (0) 16 58 90 45

+32 (0) 16 50 90 45

France

01 43 25 01 50

01 43 25 01 60

Italy

02 36 00 65 93

02 36 00 65 94

Germany

0241 6085 13140

0241 6085 33033

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Last modified: feb-07