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Ewing's sarcomacontains CCAP BACs that span the known breakpoint regions
In excess of 90% of Ewing's sarcomas contain a t(11;22) translocation
which fuses the EWS gene on chromosome 22 with the FLI1 gene on
chromosome 11. This genetic feature defines the Ewing's family of tumors
(Ewing's sarcomas, peripheral primitive neuroectodermal tumors (pPNET)
and Askin's tumors). In a minority of Ewing's tumors the EWS gene has a
different fusion partner including the ERG, ETV1 and the EA1F genes.
This disease specific set contains CCAP BACs that span the known
breakpoint regions in order to detect disruption of the normal sequence
using FISH.
Additionally, partial or complete trisomies have been associated with
these cancers or with the disease progression. Probes that would allow
the detection of these can be selected from the NCI CCAP collection.
Clones are provided as a live culture in a 2ml tube. Each tube contains
LB medium supplemented with 8% glycerol and the appropriate antibiotic.
we will ship your order at room temperature via express delivery. Store
the clones at -80°C
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+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45
