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CCAP human FISH-mappedwith a resolution of 1-2MB across the human genome
The Cancer Chromosome Aberration Project (CCAP), a joint initiative
supported by the NCI and NCBI, aims to develop tools that assist in the
analysis of chromosomal aberrations associated with malignant
transformation. To meet this objective, CCAP generated a set of
cytogenetically FISH-mapped BAC clones at a resolution of 1-2MB across
the human genome. The BACs have been physically mapped to the genome
using sequence tag sites (STS) and ordered using genetic linkage and/or
radiation hybrid mapping data. Additionally, these clones are FISH
mapped onto pro-metaphase spreads to allow high resolution placement,
uniform coverage of the chromosomes, and their precise positioning
relative to one another. This resource is the first collection to
effectively integrate the cytogenetic and sequence maps of the human
genome, thus facilitating the transition to molecular cytogenetics1
.
The CCAP FISH-mapped BACs are linked to databases containing clinical
data and histopathologic information. Additionally, links are provided
to databases containing associated genomic and genetic data such as end
sequence or gene information. Thus once a region or BAC clone of
interest is identified you can quickly and easily correlate your data
with that of others.
To find a BAC clone covering a particular region:
Individual clones:
Clones are provided as a live culture in a 2ml tube. Each tube contains LB medium supplemented with 8% glycerol and the appropriate antibiotic. Within 4-6 days of receiving your order we will ship your clone at room temperature via express delivery. Store the stock clone at -80°C.
Clone Collections:
Orders of 50 clones or greater and stock plates will be provided in 96-well microtiter plates. These will ship on dry-ice via overnight delivery and should be stored at -80°C immediately upon receipt. Please contact our customer service department for a quote and estimated shipping time on bulk orders.
1 Integration of cytogenetic landmarks into the draft
sequence of the human genome.
Nature. 2001 Feb 15;409(6822): 953-8. http://www.ncbi.nlm. nih.gov/genome/cyto/hbrc.shtml Cheung VG, Nowak N, Jang W, Kirsch IR, Zhao S, Chen XN, Furey TS, Kim UJ, Kuo WL, Olivier M, Conroy J, Kasprzyk A, Massa H, Yonescu R, Sait S, Thoreen C, Snijders A, Lemyre E, Bailey JA, Bruzel A, Burrill WD, Clegg SM, Collins S, Dhami P, Friedman C, Han CS, Herrick S, Lee J, Ligon AH, Lowry S, Morley M, Narasimhan S, Osoegawa K, Peng Z, Plajzer-Frick I, Quade BJ, Scott D, Sirotkin K, Thorpe AA, Gray JW, Hudson J, Pinkel D, Ried T, Rowen L, Shen-Ong GL, Strausberg RL, Birney E, Callen DF, Cheng JF, Cox DR, Doggett NA, Carter NP, Eichler EE, Haussler D, Korenberg JR, Morton CC, Albertson D, Schuler G, de Jong PJ, Trask BJ.
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+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45
