|
|
B-cell (IgH) leukemia & lymphomacontains CCAP BACs that span the known breakpoint regions
Many sub-types of B-cell leukemias are associated with chromosomal
translocations involving the Immunoglobulin heavy chain gene (IgH@) on
chromosome 14q32. Because of the somatic rearrangement of the IgH gene
that occurs normally, this area can accidentally associate with a
proto-oncogene in a chromosomal translocation, thus activating it, and
resulting in a B-cell neoplasia. Similarly, the translocation of
Immunoglobulin light chain Kappa and Lambda genes can also result in
B-cell neoplasms. Below is a table of genes involved in these
translocations. This disease specific set contains CCAP BACs that span
the known breakpoint regions in order to detect disruption of the normal
sequence using FISH.
Clones are provided as a live culture in a 2ml tube. Each tube contains
LB medium supplemented with 8% glycerol and the appropriate antibiotic.
we will ship your order at room temperature via express delivery. Store
the clones at -80°C.
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45
