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With the ULTRAN® - Slice Membrane Cassette System volumes
between 1 and 25 L may be processed. For this, ultra- and
microfiltration cassettes equipped with special high flux filtration
membranes and working in crossflow modes are used. The Slice system is
designed with up-scaling in mind. The retentate path length of the
ULTRAN - Slice cassette exactly corresponds in geometry with the ULTRAN
- Pilot cassettes, thus enabling linear up-scaling to pilot and
production scales.
The stainless steel filter holder is free of weld seams and the
transition to commercially available Tri-Clamp connections is provided
by a newly developed type of connection joint that guarantees
ferrite-free and corrosion-free contact surfaces. This is of special
importance when working with buffer solutions containing salt
concentrations.
Cassette Configurations
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| > ULTRAN - weld seam
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Two cassette configurations are offered which differ in their
retentate channel design. With Screen cassettes the channel is filled
with a polymeric screen which creates turbulent flow at the membrane's
surface, thus preventing gel layer formation and providing a constant
filtration rate. This configuration is suitable for molecular soluted
biomolecules
The open configuration of the so-called open channel cassettes is
provided by spacers allowing for filtration even with particle loaded
product flows. This configuration is particularly suitable for
applications such as cell harvesting, particulate removal and filtration
of highly viscous solutions.
Applications
- Concentration and desalination of antibodies, enzymes, and other
proteins
- Concentration and buffer exchange of chromatographic fractions
- Continuous buffer exchange
- Virus concentration
- Clarification of lysates
- Cell harvesting
- Concentration of colloidal suspensions
- Retention of suspended solids
| ULTRAN - Slice System |
| Number of cassettes |
1-5 |
| Membrane area per cassette |
0.1 m2 |
| Membrane material |
Polyethersulfone, hydrophilic (PES) |
| Connections |
3/4''-Tri-Clamp |
| Housing material |
Stainless steel 1.4539 |
| Hold-up volume of the retentate per
cassette |
15 mL |
| Minimal Hold-up volume of the system |
100 mL |
| Recommended operating pressure |
0.3 - 5.5 bar |
| Dimensions of the filter holder (WxLxH) |
23 x 8 x 18 cm |
| Weight |
10 kg |
| Ordering Information - ULTRAN
- Slice PES Membrane Cassettes |
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Catalogue Number |
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| Ultrafiltration |
| Cut-off |
Screen Channel |
Open Channel |
| 5 kD |
10 478 610 |
– |
| 10 kD |
10 478 620 |
– |
| 30 kD |
10 478 630 |
– |
| 50 kD |
10 478 640 |
– |
| 100 kD |
10 478 650 |
– |
| 300 kD |
– |
10 478 665 |
| 500 kD |
– |
10 478 675 |
| Microfiltration |
| Pore size |
Screen Channel |
Open Channel |
| 0.20 µm |
– |
10 478 685 |
| 0.45 µm |
– |
10 478 695 |
Intermediate sizes may be custom-made.
| Ordering Information - ULTRAN
- Slice System and Equipment |
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Catalogue Number |
| Stainless steel filter holder ULTRAN -
Slice |
10 478 303 |
| Fitting set 1: consisting of 2 T-pieces
with screw-in manometers, tubing nipples, clamps and gaskets |
10 479 952 |
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| Fitting set 2: consisting of 2 GMP
conform pressure gauges, tubing nipples, clamps and gaskets |
10 479 953 |
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| Torque wrench ( 0 - 10 Nm) |
10 478 327 |
| Peristaltic pump VL 1000 basic H53-1 |
10 478 240 |
| Peristaltic pump VL 1000 basic H53-2 |
10 478 242 |
| Peristaltic pump VL 1000 control H53-1 |
10 478 244 |
| Peristaltic pump VL 1000 control H53-2 |
10 478 246 |
| Tubing saddle is not included |
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| Tubing Saddle 6.4 x 1.6 mm |
10 478 252 |
| Tubing Saddle 9.5 x 2.4 mm |
10 478 254 |
| 4-piston-membrane pump QF 1000 S
right/left |
10 479 752 |
| 4-piston-membrane pump QF 1000 S
top/left |
10 479 753 |
| PharMed tube 6.4 x 1.6 mm (7.5m) |
10 471 813 |
| PharMed tube 9.5 x 2.4 mm (7.5m) |
10 471 820 |
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+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45