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> ULTRAN -
pilot filter holder |
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With the ULTRAN® -Pilot Membrane Cassette System
volumes between 5 and 1000 litres may be processed. For this,
ultra- and microfiltration cassettes equipped with special high
flux filtration membranes and working in crossflow modes are
used.
Designed for pilot and production scale the retentate path
length of the ULTRAN - Pilot cassette exactly corresponds in
geometry with the ULTRAN - Pilot cassette, thus enabling linear
down-scaling to laboratory scale.
The stainless steel filter holder is free of weld seams and
the transition to commercially available Tri-Clamp connections
is provided by a newly developed type of connection joint that
guarantees ferrite-free and corrosion-free contact surfaces.
This is of special importance when working with buffer solutions
containing salt concentrations.
Cassette Configurations
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> ULTRAN - weld
seam free connections |
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Two cassette configurations are offered which differ in their
retentate channel design. With Screen cassettes the channel is
filled with a polymeric screen which creates turbulent flow at
the membrane's surface, thus preventing gel layer formation and
providing a constant filtration rate. This configuration is
suitable for molecular soluted biomolecules
The open configuration of the so-called open channel
cassettes is provided by spacers allowing for filtration even
with particle loaded product flows. This configuration is
particularly suitable for applications such as cell harvesting,
particulate removal and filtration of highly viscous solutions.
Applications
- Concentration and desalination of antibodies, enzymes,
and other proteins
- Concentration and buffer exchange of chromatographic
fractions
- Continuous buffer exchange
- Virus concentration
- Clarification of lysates
- Cell harvesting
- Concentration of colloidal suspensions
- Retention of suspended solids
| ULTRAN - Pilot System |
| Number of cassettes |
1-10 |
| Membrane area per cassette |
0.45 m2 |
| Membrane material |
Polyethersulfone, hydrophilic
(PES) |
| Connections |
1 ''-Tri-Clamp |
| Housing material |
Stainless steel 1.4539 |
| Hold-up volume of the retentate
per cassette |
75 mL |
| Minimal Hold-up volume of the
system |
2 L |
| Recommended operating pressure |
0.3 - 5.5 bar |
| Dimensions of the filter holder
(WxLxH) |
26 x 25 x 30 cm |
| Weight |
38 kg |
| Ordering Information
- ULTRAN - Pilot PES Membrane Cassettes |
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Catalogue Number |
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| Ultrafiltration |
| Cut-off |
Screen Channel |
Open Channel |
| 5 kD |
10 478 710 |
– |
| 10 kD |
10 478 720 |
– |
| 30 kD |
10 478 730 |
– |
| 50 kD |
10 478 740 |
10 478 745 |
| 100 kD |
10 478 750 |
– |
| 300 kD |
– |
10 478 765 |
| 500 kD |
– |
10 478 775 |
| Microfiltration |
| Pore size |
Screen Channel |
Open Channel |
| 0.20 µm |
– |
10 478 785 |
| 0.45 µm |
– |
10 478 795 |
Intermediate sizes may be custom-made.
| Ordering Information
- ULTRAN - Pilot System and Equipment |
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Catalogue Number |
| Stainless steel filter holder
ULTRAN - Pilot |
10 478 302 |
| Fitting set Pilot:consisting of
2 GMP conform pressure gauges ( 0-6 bar), 1 diaphragm
valve, tubing nipples, clamps and gaskets |
10 479 959 |
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| Torque wrench ( 8 - 40 Nm) |
10 478 324 |
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| 4-piston-membrane pump QF 1000 S
right/left |
10 479 752 |
| 4-piston-membrane pump QF 1000
S top/left |
10 479 753 |
Rotary lobe pump on request. |
+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45