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Syringeless filters
Whatman syringeless filters are pre-assembled convenient filtration devices
for removing particulates from samples. They replace syringe-coupled filtration
devices with single, disposable units. Whatman has made sample preparation
easier, faster and more efficient with its innovative product line of
syringeless filters.
Product Navigation
Autovial®_syringeless_filters
Mini-UniPrep™_syringeless_filters
UniPrep™_syringeless_filters
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Autovial® syringeless
filters
Autovial Syringeless Filters are preassembled filtration devices
for removing particulates from samples. They replace
syringe-coupled filtration devices with single, disposable
units.
Autovial devices are comprised of two parts: a graduated
filter barrel and a plunger. The proven design features an
integral filter, built-in air purge and a support stand that
protects the recessed slip-luer tip. They are available in a 5
mL and 12 mL volume capacity.
The Autovial filter is selected according to membrane
compatibility with the sample. In practice, the sample is poured
into the 5mL or 12mL capacity filter barrel. A plunger is
inserted into the barrel until the bottom is securely in place;
there is a gap of air between the sample and plunger. Then, the
tip of the Autovial is placed into the mouth of an autosampler
vial or container and the plunger compressed. Filtration begins
immediately and, as the plunger is compressed until it reaches
the bottom, the membrane is purged with air for maximum sample
recovery. For direct instrument injection, a needle is placed on
the Autovial slip-luer outlet.
Features and Benefits
- Single unit convenience saves time
No assembly required-easier to load
- Choice of filter media. Compatible with a wide range of
sample types
- Ideal for hazardous samples. Self contained device
eliminates risk of filter pop-off
- Built-in air purge maximizes sample recovery
- Sterile option available to maintain sample integrity
- Unique prefilters design for difficult-to-filter samples
Autovial membranes are available for various applications:
- CA: Cellulose Acetate - low nonspecific protein binding
and high loading capacity membrane for biological solutions
- GMF: Glass Microfibre depth filter for samples in
aqueous or organic solutions
- NYL: Nylon membrane for aqueous and organic samples
within a pH range of 3-10
- PTFE: Polytetrafluorethylene - Teflon® membrane for
samples with > 50% organic solvent
- PVDF: Polyvinylidene Fluoride - low nonspecific protein
binding membrane for samples in aqueous solutions and/or
organic solvents
- PSU: Polysulfone – low nonspecific protein binding
membrane for samples in aqueous solutions
Patent # 4,859,336
| Typical Data -
Autovial |
| |
Autovial 5 |
Autovial 12 |
| Housing |
Polypropylene |
Polypropylene |
| Filtration Area |
1.7 cm2 |
3.0 cm2 |
| Capacity |
5 mL |
12 mL |
| Volume 'Hold Up' |
30 µL |
140 µL |
| Outlet Connection |
Male slip luer |
Male slip luer |
| Autoclavable |
121°C for 20 minutes |
121°C for 20 minutes |
| Ordering Information
- Autovial |
| Autovial 5 |
| |
Catalog Number |
Membrane |
Pore Size (µm) |
Sterile |
Quantity/Pack |
| |
AV115NPUORG |
PTFE |
0.45 |
No |
50 |
| |
AV115NPUNYL |
Nylon |
0.45 |
No |
50 |
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AV115UGMF |
GMF |
0.45* |
No |
50 |
| |
AV115NPUAQU |
PVDF |
0.45 |
No |
50 |
| Autovial 12 |
| |
Catalog Number |
Membrane |
Pore Size (µm) |
Sterile |
Quantity/Pack |
| |
AV125UGMF |
GMF |
0.45* |
No |
50 |
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AV125ENAO |
Nylon |
0.2 |
No |
50 |
| |
AV125SNAO |
Nylon |
0.2 |
Yes |
40 |
| |
AV125SORG |
PTFE |
0.2 |
Yes |
40 |
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AV125SAQU |
PVDF |
0.2 |
Yes |
40 |
| |
AV125UNAO |
Nylon |
0.45 |
No |
50 |
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AV125EPP |
PP |
0.2 |
No |
50 |
| |
AV125EORG |
PTFE |
0.2 |
No |
50 |
| |
AV125UORG |
PTFE |
0.45 |
No |
50 |
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AV125EAQU |
PVDF |
0.2 |
No |
50 |
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AV125UAQU |
PVDF |
0.45 |
No |
50 |
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AV125UCA |
CA |
0.45 |
No |
50 |
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AV125NPUAQU** |
PVDF |
0.45 |
No |
50 |
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AV125NPUPSU** |
PSU |
0.45 |
No |
50 |
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AV525UORG |
PTFE |
0.45 |
No |
1000 |
| |
AV525UAQU |
PVDF |
0.45 |
No |
1000 |
| |
AV525UNAO |
Nylon |
0.45 |
No |
1000 |
| |
AV525BGMF |
GF/B |
1 |
No |
1000 |
| Autovial
Accessories |
| Autovial Stand - 4 mL Vial Size |
AVST25040 |
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4 |
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Mini-UniPrep™ syringeless filters
Simple, Innovative, Convenient
The Whatman Mini-UniPrep Syringeless Filters, now with a new durable
plastic cap, provide a faster, easier way to remove particulates from
samples being prepared for High Performance Liquid Chromatography (HPLC)
analysis. In fact, Mini-UniPrep lets you prepare samples in one third
the time required by other methods. Add up the time savings, plus the
money saved from cutting multiple consumables out of the sample
preparation process and you'll see huge benefits for your lab.
Mini-UniPrep is a pre-assembled filtration device consisting of a
0.5ml capacity chamber and a plunger. The plunger contains a filtration
membrane at one end and a pre-attached cap/septum at the other. The
plunger is pressed through the sample in the outer chamber and positive
pressure forces the filtrate into the reservoir of the plunger. Air
escapes through the vent hole until the locking ring is engaged
providing an air-tight seal. Within seconds the Mini-Uniprep can be
placed into any approved autosampler for injection into your instrument.
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Six position compressor |
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The device can be used either manually or with one of the compressor
units available. The new multi compressor can process up to 6 samples at
one time, further improving sample processing time and reducing the risk
of hand stress.
The Mini-UniPrep device is designed to fit into any autosampler designed
to accommodate 12 x 32mm vials. Alternatively the septum can be pierced
with a needle and the sample drawn off for manual injection into an
analyzer.
Features and Benefits
- All-in-one filtration process allows to process sample loads in
one-third the time
- Wide range of membrane choices from 0.2 and 0.45um pore sizes to
meet specific sample application requirements
- Compatible with most major autosamplers. Allows for speeding
processes
- Fewer consumables required. Lower costs by up to 40 percent.
Applications
- Routine analysis
- Composite assays
- Content uniformity
- Protein precipitation
- Solubility testing
- Dissolution testing
- Sample filtration
A Variety of Mini-UniPrep Filters to Meet Your Needs
In a process of continuous improvement and innovation, Whatman has
listened to customers and created a whole family of Mini-UniPrep filters
to meet specific needs. For customers using robotics to maximize
throughput, Whatman offers Slit Septa Mini-UniPrep. For customers who
need to filter light sensitive samples, there is Amber Mini-UniPrep.
Amber Mini-UniPrep Syringeless Filter
Protects samples from UV damage.
Features and Benefits
- Amber colorant prevents photo degradation of light sensitive
samples. Same colorant used in pharmaceutical containers designed to
meet USP specifications for light resistance
- Translucent amber chamber and plunger enable easy visual
inspection
Applications
- Use with any compound that requires protection from light, such
as catecholamines or vitamins
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Mini-Uniprep HPLC instrument |
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Slit Septa Mini-UniPrep Syringeless Filter
For high throughput automation.
Features and Benefits
- Slit septum cap enables Mini-UniPrep use with
current robotics on HPLC instruments for high throughput automation
- Durable yet flexible slit septum cap has been
specially designed for instruments with sensitive sampling needs.
Sample evaporation is minimal
Applications
- Use with standard robotics on HPLC instruments with sensitive
needles, allowing for higher throughput
| Choose the Right Mini-UniPrep
Filtering Media |
| Sample Type |
Suitable Mini-UniPrep Media |
| Particulate laden liquids |
Glass Microfiber (GMF) |
| Aqueous/organic samples in 3 to 10 pH
range |
Nylon (NYL) |
| General filtration media/solvent based
samples |
Polypropylene (PP) |
| Chemically aggressive solutions |
Polytetrafluoroethylene (PTFE) |
| Biological samples requiring low protein
binding media |
Polyethersulfone (PES) |
| Aqueous/organic solvents—low
non-specific protein binding media |
Polyvinylidene fluoride (PVDF) |
| Aqueous/organic solvents—high flow and
loading capacity |
Polypropylene Depth (DpPP) |
| Typical Data - Mini-UniPrep |
| Dimensions |
Equivalent in size to 12 mm x 32 mm
vials |
| Materials of Construction |
|
| Housing and Cap |
Polypropylene |
| Filter Media |
As specified |
| Septa |
PTFE coated silicone rubber |
| Filtering Capacity |
0.5 mL |
| Nominal Force Needed to Compress |
Approximately 8 psi (0.6 bar) |
| Maximum Operating Temperature |
120°F (50°C) |
| Ordering Information |
Mini-UniPrep Syringeless
Filtration System
Standard Cap - Translucent Housing |
| Catalog Number |
Pore Size (µm) |
Media |
Quantity/Pack |
| UN203NPEAQU |
0.2 |
PVDF |
100 |
| UN203NPENYL |
0.2 |
Nylon |
100 |
| UN203NPEORG |
0.2 |
PTFE |
100 |
| UN203NPEPES |
0.2 |
PES |
100 |
| UN203NPEPP |
0.2 |
PP |
100 |
| UN203NPUAQU |
0.45 |
PVDF |
100 |
| UN203NPUDPP |
0.45 |
Dp PP |
100 |
| UN203NPUGMF |
0.45 |
GMF |
100 |
| UN203NPUNYL |
0.45 |
Nylon |
100 |
| UN203NPUORG |
0.45 |
PTFE |
100 |
| UN203NPUPES |
0.45 |
PES |
100 |
| UN203NPUPP |
0.45 |
PP |
100 |
| UN503NPEAQU |
0.2 |
PVDF |
1000 |
| UN503NPENYL |
0.2 |
Nylon |
1000 |
| UN503NPEORG |
0.2 |
PTFE |
1000 |
| UN503NPEPES |
0.2 |
PES |
1000 |
| UN503NPEPP |
0.2 |
PP |
1000 |
| UN503NPUAQU |
0.45 |
PVDF |
1000 |
| UN503NPUDPP |
0.45 |
Dp PP |
1000 |
| UN503NPUGMF |
0.45 |
GMF |
1000 |
| UN503NPUNYL |
0.45 |
Nylon |
1000 |
| UN503NPUORG |
0.45 |
PTFE |
1000 |
| UN503NPUPES |
0.45 |
PES |
1000 |
| UN503NPUPP |
0.45 |
PP |
1000 |
Mini-UniPrep with Slit
Septa for Automated Samples
Slit Septa Cap - Translucent Housing |
| Catalog Number |
Pore Size (µm) |
Media |
Quantity/Pack |
| US203NPEAQU |
0.2 |
PVDF |
100 |
| US203NPENYL |
0.2 |
Nylon |
100 |
| US203NPEORG |
0.2 |
PTFE |
100 |
| US203NPEPES |
0.2 |
PES |
100 |
| US203NPEPP |
0.2 |
PP |
100 |
| US203NPUAQU |
0.45 |
PVDF |
100 |
| US203NPUDPP |
0.45 |
Dp PP |
100 |
| US203NPUGMF |
0.45 |
GMF |
100 |
| US203NPUNYL |
0.45 |
Nylon |
100 |
| US203NPUORG |
0.45 |
PTFE |
100 |
| US203NPUPES |
0.45 |
PES |
100 |
| US203NPUPP |
0.45 |
PP |
100 |
| US503NPEAQU |
0.2 |
PVDF |
1000 |
| US503NPENYL |
0.2 |
Nylon |
1000 |
| US503NPEORG |
0.2 |
PTFE |
1000 |
| US503NPEPES |
0.2 |
PES |
1000 |
| US503NPEPP |
0.2 |
PP |
1000 |
| US503NPUAQU |
0.45 |
PVDF |
1000 |
| US503NPUDPP |
0.45 |
Dp PP |
1000 |
| US503NPUGMF |
0.45 |
GMF |
1000 |
| US503NPUNYL |
0.45 |
Nylon |
1000 |
| US503NPUORG |
0.45 |
PTFE |
1000 |
| US503NPUPES |
0.45 |
PES |
1000 |
| US503NPUPP |
0.45 |
PP |
1000 |
Amber Mini-UniPrep for
Light Sensitive Samples
Standard Cap - Amber Housing |
| Catalog Number |
Pore Size (µm) |
Media |
Quantity/Pack |
| UN203APEAQU |
0.2 |
PVDF |
100 |
| UN203APENYL |
0.2 |
Nylon |
100 |
| UN203APEORG |
0.2 |
PTFE |
100 |
| UN203APEPES |
0.2 |
PES |
100 |
| UN203APEPP |
0.2 |
PP |
100 |
| UN203APUAQU |
0.45 |
PVDF |
100 |
| UN203APUDPP |
0.45 |
Dp PP |
100 |
| UN203APUGMF |
0.45 |
GMF |
100 |
| UN203APUNYL |
0.45 |
Nylon |
100 |
| UN203APUORG |
0.45 |
PTFE |
100 |
| UN203APUPES |
0.45 |
PES |
100 |
| UN203APUPP |
0.45 |
PP |
100 |
| Six Position Compressor
Accessory - 1/pack |
| Catalog Number |
|
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| CR0000006 |
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UniPrep™ syringeless filters
UniPrep Syringeless Filters are preassembled filtration devices
for the filtration and storage of laboratory samples. These
devices are quick and easy to use and feature a plunger, filter
and vial in one unit. They replace syringe-coupled filtration
devices with single, disposable units.
UniPrep devices consist of two parts: a test tube and a
filter-plunger. The design incorporates a prefilter and a
membrane into the tip of the plunger. When the filter plunger is
pressed through the liquid placed in the test tube, positive
pressure forces the filtrate up into the reservoir of the
filter-plunger.
Features and Benefits
- Integral storage vial saves time and minimizes
laboratory waste
- Built-in prefilters means even difficult samples are
quick and easy to prepare
- Choice of membranes for wide sample compatibility
Applications
- Sample Preparation
- Difficult-to-filter samples
- Quick filtration of samples
The UniPrep Syringeless Filter is selected based on
compatibility with the sample in use. A UniPrep stand is
employed to hold the 5ml capacity test tube into which the
sample to be filtered has been poured. In manual operation, the
filter-plunger, after the tip comes in contact with the liquid,
is slowly pushed into the test tube until it stops at the
bottom. The UniPrep is emptied either by decanting into a sample
or autosampler vial or by drawing the filtered sample into a
syringe for manual injection into an instrument.
UniPrep membranes are available for various applications:
- GMF: layered glass microfibre depth filter for use with
samples containing aqueous organic solvents
- NYL: naturally hydrophilic membrane for filtration of
samples containing aqueous or organic solvents with a pH
range of 3-10
- PTFE: chemically inert Teflon® membrane for filtration
of samples containing > 50% organic solvent
- PVDF: low protein binding membrane for filtration of
samples with aqueous or aqueous/organic solvent composition
Accessories
Processor™
The Processor is a batch filtration system that simultaneously
compresses multiple Whatman filtration devices, such as the
UniPrep Syringeless Filters. For example, it can automatically
compress as many as 24 UniPrep devices. And since there is no
assembly required, your time savings is even greater.
Convenient Filtration
The Processor features unattended filtration. Place your samples
in the stand, push a button, and the Processor does all of your
filtration work. It automatically resets when the filtration is
complete.
Versatile Filtration
The Processor´s compression rate is adjustable, allowing you to
choose the speed best suited to the viscosity and particulate
load of your sample-slower for dirtier samples, faster for
cleaner ones. U.S. Patent Nos. 4,800,020 Whatman Inc., 4,832,850
and 4,897,193
| Typical Data -
UniPrep |
| Housing |
Polypropylene |
| Filtration Area |
0.3 cm2 |
| Capacity |
1–5 mL |
| Volume 'Hold Up' |
50 µL |
| Autoclavable |
121°C for 20 minutes |
| Ordering Information
- UniPrep |
| UniPrep |
| |
Catalog Number |
Membrane |
Pore Size (µm) |
Sterile |
Quantity/Pack |
| |
UN113EORG |
PTFE |
0.2 |
No |
50 |
| |
UN113UORG |
PTFE |
0.45 |
No |
50 |
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UN113UNYL |
Nylon |
0.45 |
No |
50 |
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UN113UGMF |
GMF |
0.45* |
No |
50 |
| |
UN113EAQU |
PVDF |
0.2 |
No |
50 |
| |
UN113UAQU |
PVDF |
0.45 |
No |
50 |
| |
UN113ENYL |
Nylon |
0.2 |
No |
50 |
| UniPrep
Accessories |
| UniPrep Stand |
UN0000001 |
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1 |
*Particle Retention Rating
** No prefilter |
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+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45
