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In-line filters

Whatman In-Line Filters feature a high purity polypropylene housing to maintain sample purity and are available with a choice of filtration media to suit a range of aqueous and organic samples. They utilize the most advanced construction methods and design features. This level of engineering provides for the finest disposable in-line filter devices.

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Aqueous_IFD™_and_Solvent_IFD™

Polydisc™_filters

 

 

In-line filters
> In-Line filter degasser
Aqueous IFD™ and Solvent IFD™
Whatman in-line filter/degassers (IFD) connect directly into an HPLC line to simultaneously filter and degas the mobile phase as it is being used. The Aqueous IFD provides pure filtration of aqueous based HPLC mobile phases while the Solvent IFD is used with organically based HPLC mobile phases. Specifically, the Aqueous IFD is designed to work with mobile phases containing at least 20% of the aqueous component. 

 

The Aqueous IFD has a 0.2 µm hydrophilic nylon membrane for use with aqueous-based mobile phases. Solvent IFD has a 0.2 µm high flow polypropylene membrane for mobile phases containing organic solvents. Both devices have a polypropylene housing, the circumference of which is sealed by a security ring, fittings to accommodate 1/16"-1/8" tubing and an air vent on the inlet with luer lock cap to enable priming.

The in-line filters work on the principle of "bubble point" - the point of pressure at which gasses will pass through a wet membrane. If pressure is maintained below the bubble point, the gas will not pass through the membrane and is trapped by the particular filter device.

Features and Benefits
 

  • Faster than traditional methods of mobile phase preparation-saving time in the laboratory
  • Enhanced laboratory safety
  • No need to purchase expensive degassing equipment
  • Rugged, chemically resistant polypropylene construction
  • Air vent on inlet with luer lock cap
  • Integrity testable (Bubble Point method)

Applications

  • HPLC analysis
  • Pharmaceutical research
  • Analytical chemistry

 

Typical Data
  Aqueous IFD Solvent IFD
Bubble Point1    
bar 2.9 (a) 0.76 (b)
psi 42 (a) 11.0 (b)
Maximum Flow Rate2 2.5 mL/min 2.5 mL/min
Filtration Area 16 cm2 16 cm2

1 Typical values determined with (a) water and (b) isopropanol.
2 For effective gas bubble removal in HPLC.

 

Ordering Information - In-line Filters
Catalogue Number Description Pore Size (µm) Diameter (mm) Filter Media Quantity/Pack
6726-5002 Aqueous IFD* 0.2 Nylon 10
6725-5002 Solvent IFD* 0.2 PP 10
6726-5002A Aqueous IFD** 0.2 50 Nylon 10
6725-5002A Solvent IFD** 0.2 50 PP 10
6726-5000 IFD End Fitting Kit
(10 rings and 10 caps)
10

* O-rings included: 1/32" - 5/32" ; accepts different diameter tubing 0.8mm-4mm.
** Non o-ring style—accepts 1/8" tubing only.

 

Polydisc™ filters
Whatman Polydisc 50 mm in-line disc filters are designed for larger volume sample filtration in the laboratory, at a pilot plant or in manufacturing. They are extremely versatile and cost effective. Sample volumes up to 1 liter can be filtered with one device. Polydisc devices can be used in conjunction with a syringe or connected in-line (6-10 mm ID hose) via stepped hose barbs.

 

Polydisc filters feature a high purity polypropylene housing to maintain sample purity and are available with a choice of filtration media to suit a range of aqueous and organic samples. The devices are autoclavable and sterile options are available.

 

In-line filters
> Polydisc AS

Polydisc AS

The Polydisc AS (Aqueous Solution) family of 50 mm filter devices feature a high throughput polyethersulfone membrane, which has low protein binding and no surfactants, developed for use in the pharmaceutical industry. A glass microfiber prefilter extends the life of the membrane and effectively filters heavily contaminated samples. Each Polydisc AS device has a sterility cap on the outlet and is sealed in its own "medical grade" clear blister pack, radiation sterilized and secured in a protective shelf pack.

Features and Benefits
 

  • Radiation sterilized. No EtO residuals
  • Barbed hose connections fit multiple tubing sizes
  • Integrity testable (bubble point method)
  • Lightweight (11.5 grams); avoids the collapsing of tubing which can be caused by heavy filter devices

Applications

  • Tissue culture media
  • Reagent preparation
  • Particle counting solutions
  • Pharmaceutical preparations

 

Technical Specifications - Polydisc AS
Description Pore Size (µm) Air Flow Rate (SLPM) Water Flow Rate* mL/minute @
    1.0 bar (14.5 psi) 0.7 bar (10 psi)
Polydisc AS 0.2 150
Polydisc AS 0.45 225
Polydisc AS 1.0 (GMF/Nylon) 625

*Liquid rating. Retention efficiency in gas streams is significantly higher.

 

In-line filters

Polydisc TF

This device features a PTFE membrane which is ideal for chemically aggressive solutions, reagents and organic solvents. This lightweight unit is particularly suitable for protective vents and for in-line filtration and isolation applications. The 1 µm device features a polypropylene prefilter for use with heavily contaminated samples.

Features and Benefits
 

  • Solvent resistant membrane
  • Chemical resistant housing
  • Hydrophobic PTFE membrane
  • Autoclavable (multiple)
  • Integrity testable (bubble point or water breakthrough pressure "in situ" methods)
  • Biosafe
  • Lightweight (11.5 grams); avoids the collapsing of tubing which can be caused by heavy filter devices

Applications

  • Pharmaceutical: vents and in-line applications
  • Biotech: sterile vents and exhausts for growth environments, in-line sterilization
  • Laboratory: clean or sterile gases, solvents, reagents, drying gases
  • Electronics: photoresists, solvents, gases for research

 

Technical Specifications - Polydisc TF
Description Pore Size (µm) Integrity Test Data* Flow Rates*
    Methanol Water Methanol Air
    Bubble Point

 
Breakthrough

 
mL/min at
0.7 bar (10 psi)
SLPM at
0.2 bar (3 psi)
    bar psi psi bar    
Polydisc TF 0.1 1.7 25 3.4 50 200 8
Polydisc TF 0.2 0.9 13 2.1 30 400 16
Polydisc TF 0.45 0.5 7 1.1 16 700 24
Polydisc TF 1.0 0.2 3 0.3 5 900 30

*Typical values

 

Polydisc HD

Excellent flow rate characteristics and ideal for filtering large volumes to 1 liter of aqueous and solvent samples. Polydisc HD is available in 5 and 10 µm retention ratings.

Features and Benefits
 

  • All polypropylene unit for aqueous and solvent samples
  • Broad solvent compatibility

Applications

  • Large volume sample preparation

 

Polydisc SPF

Contains a unique stack of filter media ideal for prefiltration of serum and other hard-to-filter solutions. Contains a glass microfiber and polysulfone membrane filter stack that effectively filters the complex particulates found in serum samples.

Applications

  • Virology, microbiology and tissue culture laboratories
  • Immunoassay methods and diagnostic standards/controls

 

Technical Specifications - Polydisc HD/SPF
Description Pore Size (µm) Air Flow Rate (SLPM) Water Flow Rate*
    1.0 bar (14.5 psi) mL/minute 1.0 bar (14.5 psi)
Polydisc HD 5.0 110 1500
Polydisc HD 10.0 140 2200
Polydisc SPF 1.0 500

*Liquid rating. Retention efficiency in gas streams is significantly higher.

 

Polydisc GW

Polydisc GW is specifically designed for filtration in trace analysis. It is an aqueous in-line filter with low background values for the determination of COD, TOC, DOC.

 

Typical Data
Housing Polypropylene (pigment free)
Filtration Area 16 cm2
Maximum Pressure 60 psi
Volume 'Hold Up' with Air Purge <0.1 mL
Connectors Stepped hose barbs for 6–10 mm ID tubing
Dimensions 46 mm x 56 mm
Weight 11.5 g
Membrane Types
SPF Glass microfiber/polysulfone
TF PTFE and polypropylene/PTFE
HD Polypropylene
AS 0.2 and 0.45 µm Glass microfiber/polyethersulfone
AS 1.0 µm Glass microfiber/Nylon

 

Ordering Information
Catalogue Number Membrane Pore Size (µm) Quantity/Pack
Polydisc AS
6724-5002 GMF/PES sterile 0.2 10
6724-5045 GMF/PES sterile 0.45 10
6724-5010 GMF/Nylon sterile 1.0 10
Polydisc TF
6720-5001 PTFE 0.1 10
6720-5002 PTFE 0.2 10
6720-5045 PTFE 0.45  
6721-5010 PP/PTFE 1.0 10
Polydisc SPF
6724-5000 GMF/GF/Polysulfone 1.0 10
Polydisc HD
6728-5050 Polypropylene 5.0 10
6728-5100 Polypropylene 10.0 10
Polydisc GW
10 463 400 Nylon/Quartz fibre 0.45 20
10 463 401 Nylon/Quartz fibre 0.45 50
 

 

 

 

For more information :: Bioxys and Gentaur BVBA :: Av. de l'Armée 68 B4 :: BE-1040 BELGIUM

Email: info@gentaur.com
 

International 

+32 (0) 16 58 90 45

+32 (0) 16 50 90 45

France

01 43 25 01 50

01 43 25 01 60

Italy

02 36 00 65 93

02 36 00 65 94

Germany

0241 6085 13140

0241 6085 33033

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Last modified: feb-07