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Conjugate release materials are critical to lateral flow assays. To
ensure strong assay performance, the conjugate must dry without damage
or aggregation and release rapidly when the sample is applied. For
consistent, reliable results involving conjugate release, diagnostic
manufacturers rely on Whatman products.
Features and Benefits
- Choice of product.
Rapid Release materials are optimized to provide improved
performance without blocking, while Standard Release materials allow
the development of proprietary blocking protocols.
- Inherently hydrophilic conjugate pads.
Do not require treatment prior to conjugate application, decreasing
time required for diagnostic kit production.
- Innovative design.
Enables the conjugate to dry as a solid phase without colloidal
system deterioration. Open structure allows rapid pad penetration by
both conjugate and sample.
- Product versatility.
Can be used as combined sample wick/conjugate release pads when
additional wicks are not desired.
Product Range and Properties
Rapid 24/Rapid 27
No additional blocking step is required, accelerating assay development
and simplifying manufacturing. Typically release more conjugate than
untreated pads, reducing reagent costs. Pads rewet rapidly and capture
line intensity is increased, significantly improving performance. Rapid
24 has higher absorption capacity and greater flexibility, while Rapid
27 has greater tensile strength.
Standard 14/Standard 17 Untreated grades ideal for conjugate
pad optimization for particularly sensitive assays. Manufactured to
enable optimization giving the same results every time. Pads rewet
quickly and naturally without requiring surfactant treatment,
facilitating simplified production. Standard 14 has higher absorption
capacity and greater flexibility, while Standard 17 has greater tensile
strength for easier manufacturing.
Standard Sizes
Reels are available in the following standard sizes:
12mm x 50m
17mm x 50m
22mm x 50m
27mm x 50m
| Typical Test Data - Conjugate
Release Materials |
| Grade |
Thickness (µm@53kPa) |
Absorption Capacity (mg/cm2) |
Max. Pore Size (µm) |
% Release of Gold Conjugate (after 90
sec) |
| Rapid 24 |
340 |
55 |
22 |
89 |
| Rapid 27 |
365 |
40 |
22 |
86 |
| Standard 14 |
355 |
55 |
23 |
75 |
| Standard 17 |
370 |
35 |
23 |
75 |
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