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Cultrex® DIVAA™ (Directed In Vivo Angiogenesis Assay)
| The Directed In Vivo
Angiogenesis Assay (DIVAA™) is the
first in vivo system for the study of angiogenesis that
provides quantitative and reproducible results. With the onset of
angiogenesis, cellular vascularization proceeds to invade the
angioreactor, and as early as nine days post-implantation, there are
enough cells to determine an effective dose response to angiogenic
modulating factors. The sleek design of the patented angioreactor
optimizes sensitivity and allows for up to four units per mouse, giving
a more controlled experiment and decreasing the number of mice required
for a study. Trevigen's DIVAA Kit is provided with FITC-Lectin for
fluorescent quantitative analysis. Optional protocols are available for
analysis with Calcein-AM and Dextran-FITC. |
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| Quantitative in
vivo angiogenesis analysis. |
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| Catalog # |
Component |
Size |
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3450-048-01
|
DIVAA™
Angioreactors |
48 |
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3450-048-02 |
DIVAA™
RGF BME* |
6 x 200 µL |
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3450-048-03 |
DIVAA™
10X Wash Buffer |
25 mL |
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3450-048-04 |
DIVAA™
FGF-2 |
100 ng/10 µL
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3450-048-05 |
DIVAA™
CellSperse |
15 mL |
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3450-048-06 |
DIVAA™
200X FITC-Lectin |
250 µg/50 µL
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3450-048-07 |
DIVAA™
25X FITC-Lectin Diluent |
400 µL |
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3450-048-08 |
Heparin Solution |
10 µL: 2 mg/ml |
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*Basement
Membrane Extract (BME) |
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| Components are stored at -20°C and
4°C. |
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| Guedez L, Rivera AM, Salloum R,
Miller ML, Diegmueller JJ, Bungay PM, Stetler-Stevenson WG:
Quantitative Assessment of Angiogenic Response by the Directed
In Vivo Angiogenesis Assay. AJP 2003, pp
1431-1439. |
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Products
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3450-048-K |
Cultrex®
DIVAA™ Kit, 48 samples |
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+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45
Cultrex® DIVAA™
Angiogenesis Assay Kit