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Chemical Product and Company Identification
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Name
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G418 Sulfate Cat# 81-108321-42-2
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Synonyms
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Antibiotic G-418, Geneticin disulfate salt,
108321-42-2
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Hazards
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Health: 1 Flammability: 0 Reactivity: 0
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Company Identification
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GENTAUR LABORATORIES Avenue de l'Armée 68
1040 Brussels, BELGIUM
Tel: +32 2 732 56 88
Fax: + 32 2 732 44 14
e-mail: info@gentaur.com
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In case of Emergency
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Call : GENTAUR Tel : +32 (0) 2 732 56 88
Out of office: Centre Antipoisons (Brussels) Tel: +32 (0) 70 245 245
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Identity Information |
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CAS
Registry Number |
108321-42-2 |
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UN (DOT) |
1541 |
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Physical/Chemical Characteristics |
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Molecular
Formular |
C20H40N4O10.
2H2SO4 |
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Structure |
 |
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Appearance |
Odourless,
white to off-white powder |
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Molecular weight |
692.7 |
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Potency
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> 650µg/mg |
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BIOLOGICAL POTENCY TEST ED50
Sensitivity assay |
≤400 mg / ml |
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BIOLOGICAL POTENCY TEST ED50
Resistant assay |
≥2,500 mg / ml |
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SPECIFIC ROTATION: (C=1%
in H2O at 25°C) |
+104° - +121° |
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ELEMENTAL ANALYSIS: (Based
on 4H2O) |
C: 32.3 ±
2.4 %, H: 6.7 ± 0.35 %, N: 7.5 ± 0.55 % |
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TLC |
Max. Three
spots |
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ABSORBANCE570 nm (100 mg /
ml) |
< 0.10 |
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ABSORBANCE280 nm (1 mg /
ml) |
< 0.015 |
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Solubility |
Water:
50mg/ml |
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Moisture
content |
< 10.0% |
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AMMONIA |
< 1.0 % |
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Preparation Instructions |
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Working
concentration |
Since this
antibiotic is toxic for many cells, one has to determine the
optimal concentration for each cell type. |
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Recommended => < 5 µg /ml for bacteria
and algae |
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=> 300 – 500
µg/ml for animal cells |
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~ 400
µg/ml needed for selection and ~ 200 µg/ml for maintenance in
mammalian cells |
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Storage/
Stability |
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Powder |
Storage
temperature 2-8°C |
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Warning |
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For
Research Use Only. Not for drug, household or other uses. See
Material Safety Data Sheet for additional information. |
+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45