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b-Secretase
(BACE)
is a membrane-bound aspartyl protease that cleaves the
amyloid precursor protein to generate the N-terminus of the
amyloid beta (ab) peptide.
b-Secretase
has been implicated to be an excellent target for
anti-amyloid therapy for the treatment of Alzheimer’s
disease. Finding inhibitors of
b-secretase
is one of the major goals of Alzheimer’s disease drug
development.
BioVision’s
b-Secretase
Fluorometric Assay Kit provides a convenient, nonradioactive
system for detecting
b-Secretase
activity in biological and purified samples.
The kit provides active
b-secretase
as the positive control,
b-secretase
inhibitor as the negative control, as well as the optimized
substrate and buffers for convenient measurement of
b-secretase activity in mammalian samples.
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+32 (0) 16
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+32 (0) 16
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