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Chloride Indicators

Catelog Number :   
    52010
Product Name :   
     SPQ(6-methoxy-N-(3-sulfopropyl)quinolinium)

Description:

The fluorescence of SPQ is specifically quenched by chloride via collision. Therefore, chloride concentration is measured by monitoring the degree of fluorescence decrease. The dye can be loaded into cells by hypotonic shock.
  • White solid soluble in H2O and DMSO.
  • Store at 4°C. Protect from light, specially when in solution.
  • ex\em = 344nm\443nm.
  • e (344 nm, H2O) = 3,700.
  • C15H15NO4S.
  • Mwt: 281.
  • [83907-40-8]

Chemical Structure of 52010

Reference:

Engblom, A.C., et al. Neurosci. Lett. 104, 326(1989);
Chao, A.C., et al. Biophys. J. 56, 1071(1989);
Mulberg, A.E., et al. J. Biol. Chem. 266, 20590(1991).
Catelog Number :   
    52011
Product Name :   
     MQAE (N-(ethoxycarbonylmethyl)-6-methoxyquinolinium bromide)

Description:

MQAE is an improved chloride indicator that has greater sensitivity to chloride (Ksv= 200 M-1) than SPQ (Ksv=118 M-1) and higher fluorescence quantum yield. The ester group of MQAE may slowly hydrolyze inside cells, resulting in a change in its fluorescence response.
  • White solid soluble in water and DMSO
  • Store at 4°C and protect from light, especially in solution
  • ex\em= 350/460nm.
  • e (344 nm, H2O) = 2,800
  • C14H16BrNO3
  • Mwt: 326.19

Chemical Structure of 52011

Reference:

1) Am J Physiol 259, C375 (1990); 2) Anal Biochem 178, 355 (1989); 3) Anal Biochem 241, 51(1996).

 

 

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International 

+32 (0) 16 58 90 45

+32 (0) 16 50 90 45

France

01 43 25 01 50

01 43 25 01 60

Italy

02 36 00 65 93

02 36 00 65 94

Germany

0241 6085 13140

0241 6085 33033
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Last modified: feb-07