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Products Specification
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Catelog Number :
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90104 |
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Product Name :
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Aminooxy- 6)-ROX |
Description:
Aminooxy-5(6)-ROX reacts with aldehydes or ketones to a
stable hydrazone compound under mild condition. Similar to
ARP (#90073), aminooxy-5(6)-ROX can be used to label abasic
sites in damaged DNA. Figure 7.13 shows the mechanism of the
reaction. See Figure 7.9 for spectra.
- lex\lem(MeOH)
= 568/595 nm
- Dark purple solid soluble in DMF or DMSO
- Store at -20°C and protect from moisture and light
- C45H51F6N5O10
- Mwt: 935.90
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Reference: |
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Catelog Number :
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90103 |
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Product Name :
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Aminooxy-5(6)-FAM |
Description:
Our aminooxy reagents such as aminooxy-5(6)-FAM react with
aldehydes or ketones to form a stable hydrazone compound
under mild condition. Similar to ARP (# 90073),
aminooxy-5(6)-FAM can be used to label abasic sites in
damaged DNA. Figure 7.13 shows the mechanism of the
reaction. See Figure 7.3 for spectra.
- lex\lem(pH9)
= 494/521nm
- Orange solid soluble in DMF, DMSO, or pH >6.5
buffers.
- Store at -20°C and protect from moisture and light
- C30H28F3N3O10
- Mwt: 647.55
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Reference: |
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Catelog Number :
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90105 |
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Product Name :
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Aminooxy-5(6)-TAMRA |
Description:
Aminooxy-5(6)-ROX reacts with aldehydes or ketones to form a
stable hydrazone compound under mild condition. Similar to
ARP (#90073), aminooxy-5(6)-TAMRA can be used to label
abasic sites in damaged DNA. Figure 7.13 shows the mechanism
of the reaction. See Figure 7.8 for spectra.
- lex\lem(MeOH)
= 540/565 nm
- Dark red solid soluble in DMF or DMSO
- Store at -20°C and protect from moisture and light
- C36H39F6N5O10
- Mwt: 815.71
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Reference: |
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Catelog Number :
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90113 |
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Product Name :
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Aminooxy-biotin |
Description:
We developed aminooxy-biotin as an alternative to ARP ( 90073), 1-3
which is used for labeling abasic sites in damaged DNA.
Aminooxy-biotin and ARP have similar reactivity toward
aldehydes or ketones. However, aminooxy-biotin is
hydrolytically more stable than ARP, and the longer spacer
group in aminooxy-biotin should facilitate the interaction
between biotin and avidin or streptavidin. Figure 7.11 shows
the mechanism of the reaction.
- White solid soluble in DMSO
- Store at -20°C
- C19H32F3N5O6S
- Mwt: 515.55
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Chemical Structure of 90113
Reference:
1) Biochemistry 32, 8276-8283 (1993); 2)
Biochemistry 31, 3703-3708 (1992); 3) Proc Natl Acad Sci U S A.,
97, 686-691 (2000) |
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Catelog Number :
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90010 |
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Product Name :
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ANTS |
Description:
A highly negatively charged dye with an amino group that can
be coupled to an aldehyde or ketone group to form an
unstable Schiff base. The Schiff base is usually chemically
reduced by sodium borohydride (NaBH 4) or sodium
cyanoborohydride (NaB(CN)H 3) to form a stable
linkage 1. This labeling technique has been widely
used for the labeling and subsequent sequencing of
oligosaccharides and glycoproteins. The negative charges of
the dye facilitate the electrophoretic separation of the
degradation products of carbohydrate polymers.
ANTS has also been used together with
the fluorescent quencher DPX (See 80012)
for the studies of membrane fusion or permeability2.
The mixture of ANTS-DPX is minimally fluorescent initially,
but becomes increasingly more fluorescent when dilution
(i.e., membrane fusion or leakage) occurs.
Reference: Yamazaki, T, et al.
Biochemistry 29, 1309(1990).
- lex\lem
= 353nm\520nm. E = 65,000.
- Light yellow solid soluble in water and DMSO.
- Store at 4°C. Protect from light, especially when in
solution.
- C10H7Nna2O9S3.
- Mwt: 427.
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Chemical Structure of 90010
Reference:
1) Electrophoresis 12, 94(1991); 2) Anal. Biochem.
222, 270(1994).)Yamazaki, T, et al. Biochemistry 29, 1309(1990). |
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Catelog Number :
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90028 |
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Product Name :
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APTS
(8-Aminopyrene-1,3,6-trisulfonic acid, trisodium salt) |
Description:
APTS is a very useful green fluorescent dye for labeling
glycoproteins or sugar molecules in general. The labeling
occurs via reductive amination which involves the formation
of a Schiff base between the amine of APTS and the aldehyde
or ketone of the sugar, followed by the reduction of the
Schiff base linkage to a stable carbon-nitrogen bond. The
multi-anionic nature of the dye makes it ideal for the
studies of carbohydrate molecules by high resolution
capillary electrophoresis.
- lex\lem:
424/505 nm (before conjugation).
- Yellow solid soluble in water.
- Store at 4°C and protect from light.
- C16H8Na3O9S3.
- Mwt: 523.39.
- [196504-57-1]
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Chemical Structure of 90028
Reference: |
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Catelog Number :
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90073 |
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Product Name :
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ARP
(N-(Aminooxyacetyl)-N'-(D-biotinoyl)hydrazine, trifluoroacetic
acid salt) |
Description:
ARP reacts with the exposed aldehyde group formed at abasic
sites in damaged DNA, allowing the DNA to be labeled with
biotin groups. 1,2 The labeled DNA can then be
quantitated with fluorescent or enzyme-conjugated
streptavidin complexes. ARP can freely cross the cell
membranes, thus allowing detection of abasic sites in living
cells. 3 ARP is suitable for use in microplate
assays.
- White solid soluble in DMSO.
- Store at -20°C.
- C14H22F3N5O6S.
- Mwt: 445.41.
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Chemical Structure of 90073
Reference:
1) Biochemistry 32, 8276-8283 (1993); 2)
Biochemistry 31, 3703-3708 (1992); 3) Proc Natl Acad Sci U S A.,
97, 686-691 (2000). |
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Catelog Number :
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90060 |
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Product Name :
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Biocytin hydrazide |
Description:
Chemical Structure of 90060
Reference:
1) Glycoconjugate J. 9, 21(1992); 2) Anal Biochem
171, 1(1988); 3) Anal. Biochem. 170, 271 (1988); 4)Biochem. Biophys.
Res. Comm. 136, 80(1986). |
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Catelog Number :
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90111 |
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Product Name :
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Biotin-PEO4-hydrazide |
Description:
Biotin-PEO 4-hydrazide is a water-soluble biotin
derivative capable of reacting with aldehydes or ketones to
form hydrazones.
- White solid soluble in water.
- Store at 4°C.
- C21H39N5O7S.
- Mwt: 505.63.
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Chemical Structure of 90111
Reference: |
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Catelog Number :
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90108 |
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Product Name :
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5(6)-ROX cadaverine
(mixed isomer) |
Description:
ROX cadaverine can be coupled to activated carboxy groups or
sulfonyl chlorides. See Figure 7.9 for spectra.
- lex\lem(MeOH)
= 568/595 nm
- Dark purple solid soluble in DMSO or DMF
- Store at -20°C and protect from light
- C43H48F6N4O8
- Mwt: 862.58
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Reference: |
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Catelog Number :
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90106 |
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Product Name :
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5-CR110-PEO3-amine,
TFA salt |
Description:
5-CR110-PEO 3-amine has a long water-soluble PEG
spacer that separates the green fluorescent CR110 and the
amine functional group. See Figure 7.5 for spectra.
- lex\lem(MeOH)
= 502/524 nm
- Orange yellow solid soluble in DMSO, DMF, or H2O
- Store at -20°C and protect from light
- C33H34F6N4O11
- Mwt: 776.63
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Reference: |
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Catelog Number :
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90107 |
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Product Name :
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5-TAMRA-PEO3-amine,
TFA salt (tetramethylrhodamine-PEO3-amine) |
Description:
5-TAMRA-PEO3-amine has a long water-soluble PEG spacer
separating the dye and the amine functional group. The dye
can be coupled to activated carboxy groups or sulfonyl
chlorides. See Figure 7.8 for spectra.
- lex\lem(MeOH)
= 544/571 nm
- Dark purple solid soluble in DMSO, DMF, or H2O
- Store at -20°C and protect from light
- C37H42F6N4O11
- Mwt: 832.74
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Reference: |
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Catelog Number :
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92002 |
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Product Name :
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Amino-Lumitium 430
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Description:
NH Amino-Lumitium 430 is a ruthenium complex with an
aliphatic amine that can be readily coupled to a carboxy
group via standard peptide chemistry. The dye can be
efficiently excited by either UV light or visible light in
the wavelength range from 350 nm to 480 nm with bright red
emission centered around 587 nm. Ruthenium complexes such as
this one typically have luminescence lifetimes in the micro
second range and a Stokes shift over 100 nm. By using
time-resolved luminescence measurement,the combination of
long luminescent lifetime and large Stokes shift offer the
possibility for extremely sensitive detection that could
approach the sensitivity of radioactive detection.
- lex\lem(H2O)
= 350-480(broad)/587 nm
- Yellow solid soluble in DMSO or H2O
- Store at -20°C and protect from light
- C46H51Cl2N7Ru.
- Mwt: 873.92
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Reference: |
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Catelog Number :
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92000 |
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Product Name :
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Fluorescein
cadaverine |
Description:
Fluorescein cadaverine can be coupled to activated carboxy
groups or sulfonyl chlorides. See Figure 7.4 for spectra.
- lex\lem(pH9)
= 493/517 nm
- Yellow solid soluble in DMSO, DMF, or pH>6.5 buffers
- Store at -20°C and protect from light
- C30H27F6N3O9S
- Mwt: 719.61
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Reference: |
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Catelog Number :
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80018 |
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Product Name :
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Lucifer Yellow
Cadaverine |
Description:
Like Lucifer Yellow CH ( 80015 and
80016), Lucifer Yellow Cadaverine can
be used as a fixable fluorescent tracer. In addition, the
dye can be used to conjugate to carboxylic acid groups.
- lex\lem=428/536
nm.
- Yellow solid soluble in water.
- Store at -20°C and protect from light.
- C17H17K2N3O8S2.
- Mwt: 534.
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Chemical Structure of 80018
Reference:
Anal. Biochem. 211, 210(1993). |
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Catelog Number :
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90047 |
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Product Name :
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NBD-ethylenediamine |
Description:
The fluorescence of NBD is highly dependent on the
environment; it is virtually nonfluorescent in water but
becomes strongly green fluorescent in hydrophobic media.
NBD-ethylenediamine can be readily coupled to activated
carboxy groups or sulfonyl chlorides.
- lex\lem(MeOH)
= 466/535 nm
- Yellow solid soluble in DMSO or DMF
- Store at -20°C and protect from light
- C8H9N5O3
- Mwt: 223.19
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Reference: |
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Catelog Number :
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90109 |
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Product Name :
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Sulforhodamine 101
cadaverine (Texas RedTM cadaverine) |
Description:
Sulforhodamine 101 cadaverine can be coupled to activated
carboxy groups or sulfonyl chlorides. See Figure 7.12 for
spectra.
- lex\lem(MeOH)
= 583/603 nm
- Dark purple solid soluble in DMSO or DMF
- Store at -20°C and protect from light
- C36H42N4O6S2
- Mwt: 690.87
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Reference: |
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Catelog Number :
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90110 |
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Product Name :
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Sulforhodamine
101-PEO3-amine (Texas RedTM -PEO3-amine) |
Description:
Sulforhodamine 101-PEO 3-amine has a long
water-soluble spacer separating the dye and the amine group.
The dye can be coupled to activated carboxy groups or
sulfonyl chlorides. See Figure 7.12 for spectra.
- lex\lem(MeOH)
= 583/603 nm
- Dark purple solid soluble in DMSO or DMF
- Store at -20°C and protect from light
- C39H48N4O9S2
- Mwt: 780.95
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Reference: |
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Catelog Number :
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92001 |
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Product Name :
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Tetramethylrhodamine cadaverine (mixed isomers)
(5-(and-6-)-((N-(5-aminopentyl)amino)carbonyl)tetramethylrhodamine) |
Description:
Tetramethylrhodamine cadaverine can be coupled to activated
carboxy groups or sulfonyl chlorides. See Figure 7.8 for
spectra.
- lex\lem
(MeOH) = 544/571 nm
- Dark purple solid soluble in DMSO or DMF
- Store at -20°C and protect from light
- C30H34N4O4
- Mwt: 514.62
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Reference: |
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Catelog Number :
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92016 |
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Product Name :
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INA
(5-iodonaphthyl-1-azide) |
Description:
INA is a lipophilic photoreactive probe, which has been used
to selectively label membrane-embedded cysteine residues of
proteins. 1
- Light yellow solid soluble in DMSO or DMF
- Store at -20°C and protect from light
- C10H6IN3
- Mwt: 295.08
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Reference:
1) Proc. Natl. Acad. Sci. USA 100, 886(2003). |
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+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45