Product Details: Anti-Excision Repair Cross Complement
(ERCC2). IgG fraction (monoclonal)
Basic Information
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| Product ID: |
TM-021Z-55 |
| Product Name: |
Anti-Excision Repair Cross Complement
(ERCC2). IgG fraction (monoclonal) |
| Unit: |
150µg |
| Category: |
Proteins and Antibodies for
Transcription Research |
| Subcategory: |
Proteins and Antibodies |
Product Details
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| Description: |
IgG fraction from mouse monoclonal
antibody (clone 2A10/E2) obtained by immunization of
mice with a peptide of ERCC2 (80 kDa subunit of TFIIH).
The IgG fraction was purified using Protein G-Sepharose.
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| Isotype: |
IgG1 |
| Biological Activity: |
This antibody can be used for ELISA
assay (1:8,000 dilution). It recognizes ERCC2 subunit of
TFIIH and it has not cross reaction with ERCC3 subunit.
ERCC2 is an ATP-dependent 5’-3’ DNA helicase, component
of the core-TFIIH transcription factor. It is involved
in nucleotide excision repair of DNA by opening around
the damage, and the initiation of transcription
catalyzed by RNA polymerase II.
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| Formulation: |
Solution at 0.5 mg/mL in PBS |
| Storage Conditions: |
Store at -20oC |
| Stability: |
Stable for at least one year. Avoid
repeated freezing and thawing. |
| Temperature: |
-20°C |
| References: |
Schultz, P. et. al. (2000) Cell 105,
599 - 607.
Reardon, J.T. et. al. (1996) Proc. Natl. Acad. Sci. USA
93 6482-
6487.
Drapkin, R. et al (1994) Nature 368, 769 - 772. |
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+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45