Product Details: Anti-human Complement Activation Blocker-2
(CAB-2). IgG fraction (monoclonal)
Basic Information
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| Product ID: |
MA-1301-5 |
| Product Name: |
Anti-human Complement Activation
Blocker-2 (CAB-2). IgG fraction (monoclonal) |
| Unit: |
100µg |
| Category: |
Growth Factors, Cytokines, Receptors
and their Antibodies |
| Subcategory: |
Monoclonal Antibodies (Growth
Factors/Cytokines/Receptors) |
Product Details
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| Description: |
IgG fraction from mouse monoclonal
antibody (clone 4E5/C6) obtained by immunization of mice
with human complement activation protein blocker-2,
CAB-2 (110 kDa). The IgG fraction was purified using
Protein G-Sepharose.
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| Isotype: |
IgG1 |
| Biological Activity: |
This antibody can be used for ELISA
assay (1:2,000 dilution). CAB-2 is a soluble chimeric
protein derived from human decay accelerating factor
(CD55) and membrane cofactor protein (CD46). It inhibits
C3 and C5 convertases of both classical and alternative
pathway. It also blocks the activation of complement in
vivo.
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| Formulation: |
Solution at 0.5 mg/mL in PBS |
| Storage Conditions: |
Store at -20oC |
| Stability: |
Stable for at least one year. Avoid
repeated freezing and thawing. |
| Temperature: |
-20°C |
| References: |
Higgins, P.J. et. al. (1997) J.
Immunol. 158, 2872 - 2881 |
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+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45