Product Details: Human transforming growth factor beta-2
(TGF - beta-2) recombinant
Basic Information
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| Product ID: |
GF-240-2 |
| Product Name: |
Human transforming growth factor beta-2
(TGF - beta-2) recombinant |
| Unit: |
5µg |
| Category: |
Growth Factors, Cytokines, Receptors
and their Antibodies |
| Subcategory: |
Growth Factors/Cytokines/Enzymes |
Product Details
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| Description: |
Human Transforming Growth Factor beta2
(TGF- beta2) is stimulatory for cells of mesenchymal
origin and inhibitory for cells of epithelial or
neuroectodermal origin. Mature TGF- beta2 is a
disulfide-linked homodimer of two chains composed of 112
amino acid residues each. There is a 70% homology
between human TGF- beta2 and human TGF- beta1.
Human TGF- beta2 is produced in genetically
engineered e. coli bacteria, and purified by sequential
chromatography.
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| Molecular Weight: |
25 KDa (dimeric protein) |
| Biological Activity: |
The biological activity of human TGF-&#
beta2 is determined by measuring the acidification of
the culture medium (Rat-1 cells) exposed to the growth
factor.
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| Formulation: |
1 mg/ml (pH 2.5). CAUTION: Since the
volume supplied is small, we advise our customers to
dilute this material to a working stock solution. To
remove partial aliquots in not recommended. |
| Purity: |
Over 98% pure by non-reduced SDS gel
electrophoresis. |
| Storage Conditions: |
Store at -80°C. |
| Stability: |
Several months at -80°C. |
| Temperature: |
-80°C |
| References: |
1. Moustakas, A., Lin, H.Y., Henis,
Y.I., Plamondon, J., O'Conner-McCourt, M.D., and Lodish,
H.F., (1993) The Journal of Biological Chemistry, Vol
268, 30, October, 22215-22218.
2. Geiser, A.G., Burmester, J.K., Webbink, R., Roberts,
A.B., and Sporn, M.B., (1992). The Journal of Biological
Chemistry, Vol 267, 4, February, 2588-2593. |
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58 90 45 
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