Product Details: Insulin-like Growth Factor (IGF-I) human
(RECOMBINANT)
Basic Information
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| Product ID: |
GF-050-8 |
| Product Name: |
Insulin-like Growth Factor (IGF-I)
human (RECOMBINANT) |
| Unit: |
500µg |
| Category: |
Growth Factors, Cytokines, Receptors
and their Antibodies |
| Subcategory: |
Growth Factors/Cytokines/Enzymes |
Product Details
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| Description: |
Human IGF-I is a potent mitogen for
mesenchymally-derived cells. It is composed of 70 amino
acid residues, and is 62% homologous with human IGF-II.
Human IGF-I is produced by genetically engineered
yeast, and purified by sequential chromatography.
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| Molecular Weight: |
7.5 KDa |
| Biological Activity: |
The material is active in a
receptor-binding assay using a membrane preparation from
placenta.
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| Formulation: |
Lyophilized powder |
| Purity: |
Over 95% pure by N-terminal amino acid
sequencing, amino acid composition, HPLC analysis, and
SDS gel electrophoresis. |
| Storage Conditions: |
Store at +4°C. Reconstitution is best
in water or buffer near neutral pH. After
reconstitution, storage in aliquots at -80°C is
recommended. |
| Stability: |
Several months, lyophilized or in
solution, at pH 6-7 and +4°C. |
| Temperature: |
+4°C |
| References: |
1. Modern Concepts of Insulin-Like
Growth Factor. Ed. E. Martin Spencer, M.D. (1991).
Elsevier Science Publ. (New York).
2 D'Ercole, A.J. (1987) J. Dev. Physiol. 9:481-495
3. Daughaday, W.H. and Rotwein, P. (1989) Endocr. Rev.
10:68-91 |
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