Product Details: Acidic Fibroblast Growth Factor (FGF 1)
human (RECOMBINANT)
Basic Information
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| Product ID: |
GF-040-3 |
| Product Name: |
Acidic Fibroblast Growth Factor (FGF 1)
human (RECOMBINANT) |
| Unit: |
10µg |
| Category: |
Growth Factors, Cytokines, Receptors
and their Antibodies |
| Subcategory: |
Growth Factors/Cytokines/Enzymes |
Product Details
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| Description: |
Acidic FGF is a mitogen for cells of
mesodermal and neuroectodermal origin, including
fibroblasts, endothelial cells, astrocytes, neuroblasts,
osteoblasts, and smooth muscle cells. This protein is
composed of 140 amino acid residues, and has a 55%
homology with basic FGF, including two conserved
cysteine residues.
Human Acidic FGF is produced by genetically
engineered yeast, and purified by heparin-Sepharose
affinity chromatography.
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| Molecular Weight: |
15.5 KDa |
| Biological Activity: |
Human acidic FGF is mitogenic for a
variety of normal cells in culture including
fibroblasts, glial cells, vascular endothelial cells.
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| Formulation: |
10 mM Tris-HCl, 1.5 M NaCl, pH 7.0
Concentration: 0.50 mg protein/ml. |
| Purity: |
Over 95% pure by HPLC analysis and SDS
gel electrophoresis. |
| Storage Conditions: |
Store at -80°C. It is also possible to
keep this protein at low pH (2-5) for a few days. |
| Stability: |
Unstable without a carrier protein like
gelatin or bovine serum albumin. It is recommended to
add some of these proteins, prior to aliquoting, for
longer storage. |
| Temperature: |
-80°C |
| References: |
1. Gimenez-Gallego et al., Biochem.
Biophys. Res. Comm.(1986) 138:611
2. Thornton et. al. (1983), Science 222, 623
3. Gospadorowicz, D. (1987) Methods Enzymol. 147:106 |
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+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45