Product Details: Interleukin-6 human (IL-6) (RECOMBINANT)
Basic Information
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| Product ID: |
CI-460-33 |
| Product Name: |
Interleukin-6 human (IL-6)
(RECOMBINANT) |
| Unit: |
25µg |
| Category: |
Growth Factors, Cytokines, Receptors
and their Antibodies |
| Subcategory: |
Growth Factors/Cytokines/Enzymes |
Product Details
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| Description: |
Human Interleukin-6 (IL-6) plays a role
in the mediation of the inflammatory and immune response
initiated by infection or injury. IL-6 acts on B cells
by stimulating differentiation and antibody secretion.
IL-6 also exhibits growth factor activity for mature
thymic or peripheral T cells, and enhances the
differentiation of cytotoxic T cells in the presence of
IL-2 or IFNt. This glycoprotein is composed of 184 amino
acid residues, and has a 42% homology with murine IL-6.
Human Interleukin-6 (RECOMBINANT) is produced in
genetically engineered Spodoptera frugiperda insect
cells (Sf9) infected with recombinant viruses, and
purified by sequential chromatography.
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| Molecular Weight: |
20-21 KDa (glycoprotein) |
| Biological Activity: |
3H-thymidine uptake by B9 murine
thymoma cell line that is IL-6 dependent.
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| Formulation: |
Frozen liquid solution (PBS) at 0.50
mg/ml (50 µl/vial) |
| Purity: |
Over 85% pure by SDS gel
electrophoresis. There is < 1ng/mg endotoxin. |
| Storage Conditions: |
Store at -80°C. |
| Stability: |
At least 1 year at -80°C. |
| Temperature: |
-80°C |
| References: |
1. Taga, T., and Kishimoto, T., (1997)
Ann. Rev. Immunology, 15, 797-819 |
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