Product Details: Interleukin-2 human (IL-2) (RECOMBINANT)
Basic Information
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| Product ID: |
CI-420-3 |
| Product Name: |
Interleukin-2 human (IL-2)
(RECOMBINANT) |
| Unit: |
10µg |
| Category: |
Growth Factors, Cytokines, Receptors
and their Antibodies |
| Subcategory: |
Growth Factors/Cytokines/Enzymes |
Product Details
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| Description: |
Human Interleukin-2 (IL-2) is a
lymphokine which biological effects include activation
and proliferation of T cells, B cells, and other
lymphokine activated killer cells. Human IL-2 is
composed of 133 amino acids, including 3 cysteine
residues, two of which are involved in a disulfide bond
essential for biological activity. Human and murine IL-2
are 62% homologous, and human IL-2 has been found to be
active on murine cell lines.
Human Interleukin-2 (RECOMBINANT) is produced in
genetically engineered Escherichia coli cells, and
purified by sequential chromatography.
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| Molecular Weight: |
15 KDa |
| Biological Activity: |
The biological activity is determined
by a lymphocyte proliferation assay and each vial
contains 160,000 IU (International units)
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| Formulation: |
Lyophilized in the presence of
stabilizer (mannitol), low levels of SDS (preventing
aggregation), and Sodium Phosphate. It can be
reconstituted in water giving a pH between 7.2-7.8.
There are no preservatives in this formulation. |
| Purity: |
Over 95% pure by SDS gel
electrophoresis. |
| Storage Conditions: |
Store at +2°C to +8°C |
| Stability: |
Several months as formulated, at +2°C
to +8°C. |
| Temperature: |
+2°C to +8°C |
| References: |
1. Gillis, S., Ferm, M.M., Ou, W., and
Smith, K.A., The Journal of Immunology, (1978) Vol 120,
No. 6, June, 2027-2032
2. Mosmann, T., Journal of Immunological Methods, (1983)
Vol 65, 55-63 |
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