The most recently discovered approach to cell
immortalization is through the expression of Telomerase
Reverse Transcriptase protein (TERT), particularly for cells
that are most affected by telomere length (e.g human). This
protein is inactive in most somatic cells, but when
hTERT is exogenously expressed, the cells are able to
maintain telomere lenghts sufficient to avoid senescence.
Analysis of several telomerase-immortalized cell lines has
verified that the cells maintain a stable genotype and
retain critical phenotypic markers.
From years of experience in cell immortalization, ABM has
developed the most comprehensive list of cell
immortalization products including plasmids, retro and
andenoviral vectors containing either hTERT or SV40 T
antigens. We also offer ready-to-use recombinant
retroviruses and adenoviruses. All these tools will make
your cell immortalization project simpler and easier than
ever before.
+32 (0) 16
58 90 45 
+32 (0) 16
50 90 45
cfu/ml)