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Mouse Monoclonal (IgG1)
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Click to enlarge
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Catalog #: G084 |
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Quantity: 100μg |
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Clone: LPL.A4 |
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Immunogen: Human LPL whole
protein |
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Specificity: Recognize
specifically Lipoprotein lipase (LPL) from human and bovine.
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Formulation: 1mg/ml in PBS, pH
7.4 with 0.05% sodium azide. Frozen liquid. |
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Storage/Stability: Stable for
one year at –20ºC from date of shipment. For maximum recovery of
product, centrifuge the original vial after thawing and prior to
removing the cap. Aliquot to avoid repeated freezing and thawing.
Aliquot will be stable at 4ºC for 3 months. |
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Application: Western blot
(1:1000) and ELISA (1:2000~5000) in lipid metabolic research.
Lipoprotein lipase (LPL) is the central enzyme in plasma
triglyceride hydrolysis and is secreted by macrophages in the
subendothelial space. Evidence has been provided that LPL
produced by macrophages in the vessel wall exerts proatherogenic
effects. The atherogenic effects of LPL have been mainly
attributed to its ability to favor lipid accumulation within
macrophages present in the atherosclerotic lesion. Recently, it
has also been shown that LPL promote the development of
atherosclerosis through facilitation of monocyte adhesion to
endothelial cells, stimulation of tumor necrosis factor alpha (TNF
) secretion and induction of vascular smooth muscle cell
proliferation.
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This product is
distributed for laboratory research only.
Caution: Not for diagnostic use. |
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