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Mouse Monoclonal (IgG1)
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Catalog #: G057 |
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Quantity: 100μg |
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Clone: H.F5 |
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Immunogen: N-terminal pepetides
1-225 aa.
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Specificity: Recognize
hungtingtin from human and mouse. |
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Formulation: 1mg/ml in PBS, pH
7.4 with 0.05% sodium azide. Frozen liquid. |
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Storage/Stability: Stable for
one year at –20ºC from date of shipment. For maximum recovery of
product, centrifuge the original vial after thawing and prior to
removing the cap. Aliquot to avoid repeated freezing and thawing.
Aliquot will be stable at 4ºC for 3 months. |
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Application: Western blot and
IHC in lipid metabolic research. Huntingtin is a 350kDa protein
that is mutated in Huntington's disease (HD). The normal
function of Huntingtin still remains uncertain but it has been
suggested that it performs a necessary housekeeping function.
The abnormal form of Huntingtin aggregates in vitro and forms
neuronal intranuclear and cytoplasmic inclusions in HD patients.
This antibody detects a 350KD band on western blots but also
detects smaller degradation products of Huntingtin in some
tissue lysates.
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This product is
distributed for laboratory research only.
Caution: Not for diagnostic use |
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